Pion’s PAMPA technology uses a range of membranes to mimic gastro-intestinal conditions, or the blood-brain or human skin barrier. It allows you to evaluate the passive permeability of APIs as well as the absorption potential of simple or complex formulations very precisely using robust models and protocols.
Pion PAMPA can be used for preformulation excipient screening;
Pion SKIN PAMPA offers a further ability for final formulation screening; comparing the performance of topical and transdermal formulations to rank order the permeability potential of those formulations.
PAMPA has a wide range of popular applications, each delivering robust and reliable results.
PAMPA Explorer Command Software is easy to interface, and is compatible out-of-the-box with the following commercially available UV readers and liquid handling robots:
Molecular Devices: SpectraMax® 190 • SpectraMax® Plus384 • SpectraMax® M5 • FlexStation® 3 • Tecan: Infinite® M200 • M1000 • BioTek: Epoch • Synergy 2/H4/HT/Mx/H1