Pion provides innovative technology, solutions, support and scientific expertise to the drug development industry. Pion empowers the pharmaceutical research community to use trusted data for the development of new and unique products that make a difference to people’s lives.
PAMPA’s 96-well plate-based patented technology by Pion allows you to predict the permeability of your compounds in vitro with far greater efficiency, while only requiring small amounts of potentially scarce material.
PAMPA delivers reliable and reproducible results via an artificial membrane, which is immobilized on a filter and placed between donor and acceptor compartments. At the start of a test, a drug is introduced into the donor compartment, either as a solid, formulation or neat solution in the form of a DMSO stock. Then, following the permeation period, the concentration of drug is measured in the donor and the acceptor compartments.